Can vaping cause a sore throat? is the most frequently requested question, hence the answer is yes. The chemicals in vape liquid might irritate and inflame the throat. Additionally, vaping can dry out the throat, causing irritation and soreness. Additionally, vaping can make pre-existing diseases like asthma and allergies worse, which can exacerbate the symptoms of a sore throat. Keeping properly hydrated and taking pauses from vaping will ease sore throat sensations.