Orlistat works by blocking an enzyme called lipase, which is responsible for breaking down dietary fats in the intestines. By inhibiting this enzyme, Orlistat reduces the absorption of dietary fat, leading to a decrease in overall calorie intake. Obelit weight loss is available both as a prescription medication and in lower doses as an over-the-counter (OTC) product. The prescription-strength version is typically recommended for individuals with a higher BMI or more severe obesity, while the OTC version is available for those looking to manage their weight. Orlistat can lead to modest weight loss when used as directed. It is most effective when combined with a reduced-calorie diet and regular exercise. On average, it may help individuals lose 5-10% of their initial body weight.